October 2020

Vaikea mutiloiva nivelpsoriaasi: Pohjoismainen PAM-tutkimus

Vaikea, mutiloiva nivelpsoriaasi (Psoriatic Arthritis Mutilans, PAM) on harvinainen tila, jota esiintyy Pohjoismaissa noin 3,7 potilaalla miljoonaa asukasta kohti. Olemme pohjoismaisessa yhteistyöryhmässä kuvanneet 67 aikuispotilaan taudin esiintyvyyttä, elämänlaatua, biomarkkereita ja röntgenmuutoksia. Potilaista noin 40 % oli joko sairauslomalla tai ennenaikaisella eläkkeellä. HLA-B*27 oli näillä potilailla yliedustettu. Röntgenmuutosten vaikeusaste korreloi artriitin kestoon ja kliiniseen haittaan.

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Vaikea mutiloiva nivelpsoriaasi: Pohjoismainen PAM-tutkimus

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