Cardiotoxicity in BRAF/MEK-Treated Melanoma: A Manageable but Underrecognized Risk
BRAF/MEK inhibitors improve survival in metastatic melanoma but carry a significant risk of cardiotoxicity. Our real-world study found a 21% incidence of LVEF-reduction in a Danish patient cohort, primarily within the first year. Most cases were reversible, underscoring the need for monitoring and individualized management.
