November 2020

Uusi eturauhassyöpäsolujen kasvun epigeneettinen säätelijä löytyi

Androgeenireseptorin kanssa vuorovaikuttava proteiini, BCOR, säätelee satojen androgeenireseptorin kohdegeenien ilmentymistä. Monet niistä ovat hyvin tärkeitä eturauhassyöpäsolujen kasvun säätelijöitä. Väitöstutkimuksessa löydetyn BCOR-proteiinin poistaminen vähensikin syöpäsolujen kasvua ja laukaisi niiden ohjelmoidun solukuoleman. Tulosten perusteella BCOR vaikuttaa mahdolliselta eturauhassyövän uudelta lääkeaineiden vaikutuskohteelta.

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Uusi eturauhassyöpäsolujen kasvun epigeneettinen säätelijä löytyi

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