January 2022

Sorafenibin terapeuttinen vaikutus maksasolusyövässä on riippuvainen LXR-reseptorin aktivaatiosta

Klassinen proteiinikinaasi-inhibiittori sorafenibi on yleisesti käytössä maksasolusyövän hoidossa. Raf-kinaasi-inhibition ja LXR-agonismin yhdistäminen on uusi lähestymistapa maksasolusyövän hoitoa kehitettäessä.

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Sorafenibin terapeuttinen vaikutus maksasolusyövässä on riippuvainen LXR-reseptorin aktivaatiosta

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